ACT-5 Intense Anti-Acne and Blemish Treatment, 30ml

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Anti-imperfection innovation with bakuchiol: enjoy the benefits of retinol without its side effects!  

ACT-5 is an exclusive combination of three active ingredients targeting the five causes and factorial consequences of moderate to severe acne in dark, matt and mixed black skins. It also works on Caucasian skin. It restores the barrier functions, prevents bacterial proliferation, smoothes the skin's texture, preserves the quality of the sebum (squalene) by protecting it from pro-inflammatory oxidation and reduces pigmentation spots due to imperfections. ACT-5 does not dry out the skin and has excellent anti-ageing qualities.

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A Nubiance lab innovation, ACT-5 is an exclusive formula initially developed for mixed to dark skin prone to acne. These skins are likely to develop brown spots resulting from post-inflammatory hyperpigmentation following acne. In use, the effectiveness of ACT-5 has proven to be remarkable whatever the ethnicity of the users and their geographical area. Therefore, ACT-5 is proposed indiscriminately for young and mature, light or dark skins, provided they are predisposed to hyperseborrhea. 

ACT-5 acts biologically on the causes and consequences of acne. The unique combination of dermatological active ingredients reteaches the skin to regulate the quality and quantity of its fatty acids, to regain a sebum close to that of healthy skin and effectively prevent the appearance of pimples and blackheads.

The effectiveness of ACT-5 is based on three complementary ingredients that act on the causes and consequences of acne and help preserve the integrity and functionality of sebum. These three ingredients are:

Sytenol® A (bakuchiol):

Acting on lipid homeostasis, bakuchiol is a natural alternative substance to retinol, a powerful lipo-peroxidation inhibitor. It ensures the preservation of sebum by opposing the oxidation of squalene, thus preventing the appearance of pro-inflammatory mediators. It inhibits the development of P acnes (Propionibacterium acnes). For more information on bakuchiol, click here.

Hydrasynol® IDL (isosorbide dilinoletate):

Patented molecule resulting from green and sustainable chemistry, it acts on the homeostasis of the skin barrier. It regulates hydration by the filaggrine route, a precursor of natural hydration factors. It contributes to the preservation of the barrier functions.

Synovea® HR (hexylresorcinol):

Powerful inhibitor of melanin production by the tyrosinase and peroxidase pathways to control post-inflammatory hyperpigmentation.

What is sebum?

Sebum, a complex lipidic compound, is essential for maintaining the skin's barrier functions and hydration. A deficit in sebum production is synonymous with xerosis or atopy, leaving the skin vulnerable to allergens and micro-organisms. 

On the contrary, hyperseborrhea provides an effective protective shield for the skin, but is nevertheless a breeding ground for acne in the event of oxidation.

Excessive sebum production is a necessary, but not sufficient condition. Indeed, the propensity of sebum to oxidise varies from one individual to another. Genetic, dietary, environmental or exogenous factors, such as pollution or the use of detergents, impact the quantity and quality of sebum.

Lipoperoxidation of squalene, a key lipid in the composition of sebum, is the beginning of a chain reaction involving follicular occlusion, hyperkeratinisation, microbial proliferation and inflammation. All of these factors are self-perpetuating and can lead to severe retentional acne.


aqua (water), oleyl erucate, c12-13 alkyl lactate, glycerin, isosorbide disunflowerseedate, myristyl myristate, c20-22 alkyl phosphate, stearyl heptanoate, c20-22 alcohols, caprylic/capric triglyceride, cellulose, stearyl caprylate, cetyl alcohol, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, bakuchiol, ethyl linoleate, hexylresorcinol, parfum (fragrance), pentaerythrityl distearate, chlorphenesin, xanthan gum, sodium hydroxide, disodium edta, peg-8, polysorbate 60, sorbitan isostearate, tocopherol, butylphenyl methylpropional, linalool, limonene, ascorbyl palmitate, hydroxyisohexyl 3-cyclohexene carboxaldehyde, hydroxycitronellal, hexyl cinnamal, soybean oil, ascorbic acid, citric acid, bht

We select the best ingredients in order to guarantee you high-performance products that respect your skin. Our products are dermatologically tested and are subject to clinical tests carried out by independent laboratories.

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4.3 /5

Based on 70 customer reviews

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Floriane P. published the 17/06/2021 following an order made on 07/05/2021


Super efficace.

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Angela A. published the 07/06/2021 following an order made on 24/04/2021


Efficace pour les boutons

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STEPHANIE M. published the 07/06/2021 following an order made on 21/04/2021


J viens de le commencer

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armel mario Jacques M. published the 07/06/2021 following an order made on 19/04/2021


Je suis convaincu qu'il est de qualité, mais je pense qu'il est trop tôt pour le dire. Je l'utilise encore

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HAMIDA U. published the 29/05/2021 following an order made on 12/03/2021


très efficace pour moi

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Jauriane P. published the 18/05/2021 following an order made on 09/04/2021


Efficace. Texture agréable

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Anaïs M. published the 23/04/2021 following an order made on 08/03/2021


Excellent produit

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Kathadje G. published the 19/04/2021 following an order made on 24/02/2021



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Laurence R. published the 19/04/2021 following an order made on 04/03/2021


Bonjour, Crème absolument parfaite :) C'est la Crème à avoir ! Plus de boutons, ni de taches. Je l'ai conseillée à ma fille Salomé. J vous remercie.

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Elise P. published the 19/04/2021 following an order made on 02/03/2021


produit à vérifier avec le temps pour l’instant ça va

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